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Roberto Ambra

Qualifica: RICERCATORE 

 

AST di afferenza: Scienze della Nutrizione

 

Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione

Roma, Italia,

via Ardeatina, 546

 

Email: ambra@entecra.it

ATTIVITÀ DI RICERCA, INFORMAZIONE E PROMOZIONE

 

Studio dei meccanismi molecolari alla base degli effetti di alcune molecole “bioattive” di interesse nutrizionale, in sistemi modelli da laboratorio, mediante:

PUBBLICAZIONI RECENTI

  1. R. Comitato, K. Nesaretnam, G. Leoni,  R. Ambra, R. Canali, Marino M, Virgili F. (2009) A novel mechanism of tocotrienol activity: involvement of ERb signaling. AJP – Endoc. Metab. (in press)
  2. Finamore, M. Roselli, S. Britti, G. Monastra, R. Ambra, A. Turrini and E. Mengheri. (2008) Intestinal and peripheral immune response(s) in mice after MON810 maize consumption. J. Agric Food Chem. 56, 11533-11539,
  3. E. Venneria, E. Finotti, S. Fanasca, R. Ambra, G. Monastra, G. Maiani. (2008) Nutritional values assessment of genetically modified Wheat, Corn and Tomato crops. J. Agric Food Chem. 56, 9206-9214.
  4. R. Canali, R. Ambra, C. Stelitano, F. Mattivi, C. Scaccini,  F. Virgili. (2007) A novel model to study the biological effects of red wine at molecular level. Br. J. Nutr. 97, 1-6.
  5. R. Ambra, S. Salvi, M. Marcelli, G. Morelli. (2006) Come un ago in un pagliaio. Sapere, 5, 22-31.
  6. F. Cimino, R. Ambra, R. Canali, A. Saija, F. Virgili. (2006) Effect of cyanidin-3-O-glucoside on UVB-induced response in human keratinocytes. J. Agric. Food Chem. 54, 4041-4047.
  7. R. Ambra, G. Rimbach, S. de Pascual Teresa, D. Fuchs, U. Wenzel, H. Daniel, F. Virgili. (2006) Genistein affects the expression of genes involved in blood pressure regulation and angiogenesis in primary human endothelial cells. Nutr. Met. Cardiovasc. Dis. 16, 35-43.
  8. D. Fuchs, S. De Pascua-Teresa, G. Rimbach, F. Virgili, R. Ambra, H. Daniel and U. Wenzel (2004) Proteome analysis for identification of target proteins of genistein in primary human endothelial cells stressed with oxidized LDL or homocysteine. Eur. J. Nutr. 44, 95-104.
  9. K. Nesaretnam, R. Ambra, K.R. Selvaduray, A. Radhakrishnan, R. Canali, F. Virgili. (2004) Tocotrienol-rich fraction from palm oil and gene expression in human breast cancer cells. Ann N.Y. Acad. Sci. 1031, 143-57.
  10. R. Ambra, K. Nesaretnam, K.R. Selvaduray, A. Radhakrishnan, K. Reimann and F. Virgili. (2004) Tocotrienols from palm oil affect gene expression in tumors resulting from MCF-7 cells inoculation in Athymic mice, Lipids 39, 459-67.
  11. R. Ambra, E. Mocchegiani, R. Giacconi, R. Canali, A. Rinna and F.Virgili. (2004) Characterization of the hsp70 response in lymphoblasts from aged and centenarians subjects and differential effects of in vitro zinc supplementation. Exp. Gerontol. 39, 1475-84.
  12. F. Virgili, F. Acconcia, R. Ambra, A. Rinna, P. Totta and M. Marino. (2004) Nutritional flavonoids modulate estrogen receptor alpha signaling. IUBMB Life 56, 145-151.
  13. R. Ambra, B. Grimaldi, S. Zamboni, P. Filetici, G. Macino and P. Ballario. (2004) Photomorphogenesis in the hypogeus fungus Tuber borchii. Isolation and characterization of Tbwc-1 a putative blue-light photoreceptor. Fung. Genet. Biol. 41, 688-697.
  14. F. Virgili, R. Ambra, F. Muratori, F. Natella, J. Majewicz, AM. Minihane and G. Rimbach. (2003) Effect of oxidised low-density lipoprotein on differential gene expression in primary human endothelial cells. Antiox. Redox Signaling 2, 237-47.

PUBBLICAZIONI DI PARTICOLARE RILEVANZA

  1. R. Comitato, K. Nesaretnam, G. Leoni,  R. Ambra, R. Canali, Marino M, Virgili F. (2009) A novel mechanism of tocotrienol activity: involvement of ERb signaling. AJP – Endoc. Metab. (in press)
  2. R. Ambra, G. Rimbach, S. de Pascual Teresa, D. Fuchs, U. Wenzel, H. Daniel, F. Virgili. (2006) Genistein affects the expression of genes involved in blood pressure regulation and angiogenesis in primary human endothelial cells. Nutr. Met. Cardiovasc. Dis. 16, 35-43.
  3. D. Fuchs, S. De Pascua-Teresa, G. Rimbach, F. Virgili, R. Ambra, H. Daniel and U. Wenzel (2004) Proteome analysis for identification of target proteins of genistein in primary human endothelial cells stressed with oxidized LDL or homocysteine. Eur. J. Nutr. 44, 95-104.
  4. K. Nesaretnam, R. Ambra, K.R. Selvaduray, A. Radhakrishnan, R. Canali, F. Virgili. (2004) Tocotrienol-rich fraction from palm oil and gene expression in human breast cancer cells. Ann N.Y. Acad. Sci. 1031, 143-57.
  5. R. Ambra, K. Nesaretnam, K.R. Selvaduray, A. Radhakrishnan, K. Reimann and F. Virgili. (2004) Tocotrienols from palm oil affect gene expression in tumors resulting from MCF-7 cells inoculation in Athymic mice, Lipids 39, 459-67.